The first of Pacino’s teamings with Levinson launched the actor on a bold new trajectory in the exploration of a trio of notorious real-life figures. The late Jack Kevorkian endorsed Pacino’s performance, which richly mines the Doctor’s professional and personal commitment to advocate euthanasia amidst considerable opposition and controversy through the 1990s. Danny Huston portrays Kevorkian’s lawyer; Brenda Vaccaro, his sister; Susan Sarandon and John Goodman, his aides.